Article
Leader of the pack: gene mapping in dogs and other model organisms.
Nature reviews. Genetics - 1 Sept 2008
Karlsson Elinor K, Lindblad-Toh Kerstin
Abstract excerpt
The domestic dog offers a unique opportunity to explore the genetic basis of disease, morphology and behaviour. We share many diseases with our canine companions, including cancer, diabetes and epilepsy, making the dog an ideal model organism for comparative disease genetics. Using newly developed resources, whole-genome association in dog breeds is proving to be exceptionally powerful. Here, we review the...
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