Article
The relevance of HPA-15 antigen expression for anti-HPA-15 antibody detection.
International journal of laboratory hematology - 1 Feb 2012
Maślanka K, Michur H, Guz K, Wróbel A, Uhrynowska M, Misiak A, Ejduk A, Brojer E, Zupańska B
Abstract excerpt
INTRODUCTION: The HPA-15 antigen system is characterized by a low antigen expression on platelets. The antibodies against this antigen are implied in fetal/neonatal alloimmune thrombocytopenia (F/NAIT), post-transfusion purpura, and refractoriness to platelet transfusions. Detection of these antibodies appears to be related to the level of HPA-15 expression on the platelets used in the monoclonal...
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