Article
Genetic variation on 9p22 is associated with abnormal ovarian ultrasound results in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial.
PloS one - 1 Jan 2011
Wentzensen Nicolas, Black Amanda, Jacobs Kevin, Yang Hannah P, Berg Christine D, Caporaso Neil, Peters Ulrike, Ragard Lawrence, Buys Saundra S, Chanock Stephen, Hartge Patricia
Abstract excerpt
BACKGROUND: A recent ovarian cancer genome-wide association study (GWAS) identified a locus on 9p22 associated with reduced ovarian cancer risk. The single nucleotide polymorphism (SNP) markers localize to the BNC2 gene, which has been associated with ovarian development. METHODS: We analyzed the association of 9p22 SNPs with transvaginal ultrasound (TVU) screening results and CA-125 blood levels from...
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