Article
A peripheral monocyte interferon phenotype in HIV infection correlates with a decrease in magnetic resonance spectroscopy metabolite concentrations.
AIDS (London, England) - 10 Sept 2011
Pulliam Lynn, Rempel Hans, Sun Bing, Abadjian Linda, Calosing Cyrus, Meyerhoff Dieter J
Abstract excerpt
OBJECTIVE: In spite of effective antiretroviral therapy (ART), cognition is impaired in upwards of 35% of the HIV-infected population. We investigated a possible link between peripheral immune activation and brain metabolite concentrations. DESIGN AND METHODS: Thirty-five HIV-seropositive (HIV+) and eight HIV-seronegative adults were recruited to this cross-sectional study. All HIV-positive patients were on ART...
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