Article
Gene expression patterns associated with neurological disease in HIV infection
2016-12-23
Abstract excerpt
To provide new insight into the pathogenesis of neurocognitive impairments (NCI) in HIV infection, we used the Gene Set Enrichment Analysis (GSEA) algorithm to analyze pathway dysregulations in gene expression profiles of HIV-infected patients with or without NCI and HIV encephalitis (HIVE). While HIVE was characterized by widespread inflammation and tissue damage, gene expression evidence of induction of interfer...
Topics
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- Advanced biosensing and bioanalysis techniques
- Alzheimer's disease research and treatments
- Bioinformatics and Genomic Networks
- HIV-related health complications and treatments
- HIV Research and Treatment
- Mosquito-borne diseases and control
- Neuroinflammation and Neurodegeneration Mechanisms
- RNA Research and Splicing
Identifiers and source
- Literature Corpus work
- 694eeeb4-e323-5f30-843a-69a75c9863f5
- DOI
- 10.1101/096172
