Article
Genetic evolution of pancreatic cancer: lessons learnt from the pancreatic cancer genome sequencing project.
Gut - 1 Jul 2012
Iacobuzio-Donahue Christine A
Abstract excerpt
Pancreatic cancer is a disease caused by the accumulation of genetic alterations in specific genes. Elucidation of the human genome sequence, in conjunction with technical advances in the ability to perform whole exome sequencing, have provided new insight into the mutational spectra characteristic of this lethal tumour type. Most recently, exomic sequencing has been used to clarify the clonal evolution of...
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