Article
β-Glucocerebrosidase gene mutations in two cohorts of Greek patients with sporadic Parkinson's disease.
Molecular genetics and metabolism - 1 Jan 2000
Moraitou Marina, Hadjigeorgiou Georgios, Monopolis Ioannis, Dardiotis Efthimios, Bozi Maria, Vassilatis Demitris, Vilageliu Lluisa, Grinberg Daniel, Xiromerisiou Georgia, Stefanis Leonidas, Michelakakis Helen
Abstract excerpt
An increasing number of clinical, neuropathological and experimental evidence linking Gaucher disease and a spectrum of synucleinopathies, including Parkinson's disease (PD) has emerged over the last decade. In particular, several studies, despite individual differences, have shown that mutations in the β-glucocerebrosidase gene (GBA) are a risk factor for PD. Recently a study from Northern Greece has shown a...
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