Article
Susceptibility of XPD and RAD51 genetic variants to carcinoma of urinary bladder in North Indian population.
DNA and cell biology - 1 Feb 2012
Sobti Ranbir Chander, Kaur Saranjeet, Sharma Vijay Lakshmi, Singh Shrawan Kumar, Hosseini Seyed Ali, Kler Rupinder
Abstract excerpt
For the present study, two polymorphisms, xeroderma pigmentosum, complementation group D (XPD) Lys751Gln and RAD51 135G/C were studied with regard to bladder cancer. For XPD Lys751Gln polymorphism, an increased risk of bladder cancer was found to be associated with the Gln variant allele (odds ratio [OR]=1.86, 95% confidence interval [CI]=1.27-2.73), on taking AA (Lys/Lys) as the referent genotype. In males, the...
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