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The Generation of Live Offspring from Vitrified Oocytes

27 Jun 2011

Abstract excerpt

Oocyte cryopreservation is extremely beneficial for assisted reproductive technologies, the treatment of infertility and biotechnology and offers a viable alternative to embryo freezing and ovarian grafting approaches for the generation of embryonic stem cells and live offspring. It also offers the potential to store oocytes to rescue endangered species by somatic cell nuclear transfer and for the generation of...

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PMID: 21738724
DOI: 10.1371/journal.pone.0021597

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The Generation of Live Offspring from Vitrified OocytesPMID 21738724Read ↗

Vitrification affects the post-implantation development of mouse embryos by inducing DNA damage and epigenetic modificationsSemantic proximity Read ↗

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Potential Importance of Vitrification in Reproductive MedicineSemantic proximity Read ↗

What impact does oocyte vitrification have on epigenetics and gene expression?Semantic proximity Read ↗

Generation of Live Offspring from Vitrified Mouse Oocytes of C57BL/6J StrainSemantic proximity Read ↗

Successful live birth from vitrified oocytes after 5 years of cryopreservationSemantic proximity Read ↗

L-carnitine supplementation during vitrification of mouse germinal vesicle stage-oocytes and their subsequent in vitro maturation improves meiotic spindle configuration and mitochondrial distribution in metaphase II oocytesSemantic proximity Read ↗

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Poor embryo development in post-ovulatory <i>in vivo</i> -aged mouse oocytes is associated with mitochondrial dysfunction, but mitochondrial transfer from somatic cells is not sufficient for rejuvenationSemantic proximity Read ↗

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