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Vitrification affects the post-implantation development of mouse embryos by inducing DNA damage and epigenetic modifications

7 Feb 2025

Abstract excerpt

Vitrification is widely used in assisted reproductive technology (ART) for female infertility, but the long-term effect on the embryo of vitrification has not been comprehensively studied. The study aimed to investigate the effect of vitrification on long-term development of mouse embryos. The warmed embryos which were frozen at 8-cell stage were cultured in vitro until the blastocyst stage and were transferred...

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PMID: 39920865
DOI: 10.1186/s13148-025-01826-y

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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