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Nuclear Transfer Preserves the Nuclear Genome of Freeze-Dried Mouse Cells

1 Jan 2008

Abstract excerpt

Mouse spermatozoa can be freeze dried without losing genetic integrity and reproductive potential. However, it is not known if freeze-dried mouse cells similarly maintain their genetic integrity and developmental potential following nuclear transfer. Here, we investigated the developmental capacity and embryonic stem (ES) cell derivation of reconstructed oocytes by nuclear transfer using freeze-dried cumulus or...

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PMID: 18854641
DOI: 10.1262/jrd.20112

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