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Mapping of Interactions between Human Macrophages and <i>Staphylococcus aureus</i> Reveals an Involvement of MAP Kinase Signaling in the Host Defense

7 Jul 2011

Abstract excerpt

Staphylococcus aureus is a dangerous opportunistic human pathogen that causes serious invasive diseases when it reaches the bloodstream. Recent studies have shown that S. aureus is highly resistant to killing by professional phagocytes and that such cells even provide a favorable environment for intracellular survival of S. aureus. Importantly, the reciprocal interactions between phagocytes and S. aureus have...

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PMID: 21736355
DOI: 10.1021/pr200224x

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