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Article

[BRCA1- and BRCA2 mutations: Clinical management of patients with hereditary breast and ovarian cancer].

Wiener medizinische Wochenschrift (1946) - 1 Apr 2010

Pristauz Gunda, Geigl Jochen B, Petru Edgar

Abstract excerpt

BACKGROUND: In total, 5-10% of all breast cancer cases are related to gen mutations. In most cases a mutation in the BRCA1-gen and BRCA2-gen is responsible for insufficient repair of DNA damages that cause breast and ovarian cancer. CLINICAL MANAGEMENT: In patients carrying BRCA1-mutation the risk for developing breast and ovarian cancer is 87% and 40% as well as 47% and 20% for those carrying a BRCA2-mutation....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20473725
DOI: 10.1007/s10354-010-0772-7

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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