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Article

Unexpected role for Helicobacter pylori DNA polymerase I as a source of genetic variability.

PLoS genetics - 1 Jun 2011

García-Ortíz María-Victoria, Marsin Stéphanie, Arana Mercedes E, Gasparutto Didier, Guérois Raphaël, Kunkel Thomas A, Radicella J Pablo

Abstract excerpt

Helicobacter pylori, a human pathogen infecting about half of the world population, is characterised by its large intraspecies variability. Its genome plasticity has been invoked as the basis for its high adaptation capacity. Consistent with its small genome, H. pylori possesses only two bona fide DNA polymerases, Pol I and the replicative Pol III, lacking homologues of translesion synthesis DNA polymerases....

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Identifiers

PMID: 21731507
DOI: 10.1371/journal.pgen.1002152
PMCID: PMC3121766

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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