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Article

DNA methylation regulates phenotype-dependent transcriptional activity in Candida albicans.

Proceedings of the National Academy of Sciences of the United States of America - 19 Jul 2011

Mishra Prashant K, Baum Mary, Carbon John

Abstract excerpt

DNA methylation is a common epigenetic signaling mechanism associated with silencing of repeated DNA and transcriptional regulation in eukaryotes. Here we report that DNA methylation in the human fungal pathogen Candida albicans is primarily localized within structural genes and modulates transcriptional activity. Major repeat sequences and multigene families are largely free of DNA methylation. Among the genes...

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Identifiers

PMID: 21730141
DOI: 10.1073/pnas.1109631108
PMCID: PMC3141964

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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