Article
A close insight to factor VIII inhibitor in the congenital hemophilia A.
Expert review of hematology - 1 Sept 2016
Tabriznia-Tabrizi Shamsoreza, Gholampour Marzie, Mansouritorghabeh Hassan
Abstract excerpt
INTRODUCTION: Hemophilia A (HA) has an X-linked pattern of inheritance and is the most common of the hemorrhagic disorders. HA is caused by a decreased or deficiency of the functional clotting factor VIII (FVIII) and effects 1 in 5000-10,000 male births. The common treatment for hemophilia is replacement therapy by plasma-derived or recombinant FVIII. Approximately 20-30% of people with a severe type of HA...
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