Cutaneous type of adult T cell leukemia/lymphoma in a French West Indian woman. Clonal rearrangement of T-cell receptor beta and gamma genes and monoclonal integration of HTLV-I proviral DNA in the skin infiltrate.

doi:10.1016/0190-9622(90)70321-8

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Article

Cutaneous type of adult T cell leukemia/lymphoma in a French West Indian woman. Clonal rearrangement of T-cell receptor beta and gamma genes and monoclonal integration of HTLV-I proviral DNA in the skin infiltrate.

Journal of the American Academy of Dermatology - 1 Nov 1990

Gessain A, Moulonguet I, Flageul B, Perrin P, Capesius C, D'Agay M F, Gisselbrecht C, Sigaux F, Civatte J

Abstract excerpt

A 45-year-old woman, a native of the French West Indies who had lived in France since 1973, developed multiple cutaneous plaques and nodules in 1987. Histopathologic studies revealed dermal infiltration with mature activated T cells (CD4+, CD25+, DR+) with nuclear convolutions and epidermatotropi...

Topics

Antigens, CD
Blotting, Southern
Cells, Cultured
DNA, Viral
Female
Gene Rearrangement, beta-Chain T-Cell Antigen Receptor
Gene Rearrangement, gamma-Chain T-Cell Antigen Receptor
HTLV-I Antigens
Human T-lymphotropic virus 1
Humans
Leukemia-Lymphoma, Adult T-Cell
Middle Aged

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Phenotype

Proviruses

Skin

Skin Neoplasms

Source

Open in PubMed

Identifiers

PMID: 2172339
DOI: 10.1016/0190-9622(90)70321-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2172339-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.