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Article

Development and Maintenance of Cancer Stem Cells under Chronic Inflammation

1 Jan 2011

Abstract excerpt

In many human cancers, tumorigenic potential is not equally shared by all cells but is restricted to phenotypically distinct subpopulations termed cancer stem cells. Cancer stem cells are also capable of both self-renewal and differentiation, and these functional properties have been suggested to play major roles in tumor initiation and progression. The factors responsible for the development of cancer stem cells...

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PMID: 21720087
DOI: 10.1272/jnms.78.138

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