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Chronic inflammation, the tumor microenvironment and carcinogenesis

1 Jul 2009

Abstract excerpt

Chronic inflammation often precedes or accompanies a substantial number of cancers. Indeed, anti-inflammatory therapies have shown efficacy in cancer prevention and treatment. The exact mechanisms that turn a wound healing process into a cancer precursor are topics of intense research. A pathogenic link has been identified between inflammatory mediators, inflammation related gene polymorphisms and carcinogenesis....

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PMID: 19550141
DOI: 10.4161/cc.8.13.8985

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