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Article

Correlation of genes associated with drug response to prognosis of large cell lung carcinoma.

Chinese journal of cancer - 1 Jul 2011

Chen Cheng, Jiang Xiang-Li, Zhang Cui-Cui, Li Kai

Abstract excerpt

Platinum-based chemotherapy remains the main treatment of advanced lung cancer. However, platinum resistance has become a major treatment obstacle. Novel therapies, particularly tyrosine kinase inhibitors of the epidermal growth factor receptor (EGFR-TKI) and agents that target vascular endothelial growth factor (VEGF), have improved the treatment. Both chemotherapy and targeted therapy have their molecular...

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Identifiers

PMID: 21718596
DOI: 10.5732/cjc.010.10503
PMCID: PMC4013425

Genes

EGFR
ERCC1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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