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Maternal Smoking and Fetal Sex Significantly Affect Metabolic Enzyme Expression in the Human Fetal Liver

30 Jun 2011

Abstract excerpt

CONTEXT: Pollutants and toxicants passing from the mother to the fetus may damage developing organ systems. The human fetal liver is both a potential target organ and a critical defense against exposure to such xenochemicals. OBJECTIVE: The aim of the study was to determine the effects of human fetal toxicant exposure, via maternal smoking, on metabolic enzyme transcripts in the fetal liver. DESIGN AND SETTING:...

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Share to Carcinogens and Genotoxicity Assessment
Share to Glutathione Transferases and Polymorphisms
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PMID: 21715529
DOI: 10.1210/jc.2011-1437

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