Article
Efficacy and safety of raltegravir in treatment-experienced HIV-1-infected patients switching from enfuvirtide-based regimens: 48 week results of the randomized EASIER ANRS 138 trial.
The Journal of antimicrobial chemotherapy - 1 Sept 2011
Gallien Sébastien, Braun Joséphine, Delaugerre Constance, Charreau Isabelle, Reynes Jacques, Jeanblanc François, Verdon Renaud, de Truchis Pierre, May Thierry, Madelaine-Chambrin Isabelle, Aboulker Jean-Pierre, Molina Jean-Michel
Abstract excerpt
OBJECTIVES: To assess the sustainable efficacy and safety of a switch from enfuvirtide to raltegravir in patients with multidrug-resistant HIV infection. METHODS: One hundred and seventy patients with multidrug-resistant HIV infection and suppressed plasma HIV RNA levels < 400 copies/mL under an enfuvirtide-based regimen were randomized to maintain their regimen or to switch to a raltegravir-based regimen...
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