Article
Long-term effectiveness of bictegravir/emtricitabine/tenofovir alafenamide in people with HIV and resistance-associated mutations.
AIDS (London, England) - 1 Oct 2026
Lamaizón Cinthia S, Cecchini Diego, Brizuela Martin, Copertari Gastón, Bacelar Brenda, Roel Macarena, Bottaro Edgardo, Cassetti Lidia I
Abstract excerpt
Resistance-associated mutations (RAMs) limit treatment options for HIV. We evaluated virologic outcomes in people with HIV harboring RAMs who switched to bictegravir/emtricitabine/tenofovir alafenamide (B/F/TAF) in a real-world cohort during 4 years of follow-up. Virologic suppression was sustained across RAM subgroups, including M184V/I with additional nucleoside reverse transcriptase inhibitor (NRTI)-RAMs....
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