Article
Switching to Elvitegravir/Cobicistat/Emtricitabine/Tenofovir Alafenamide in Adults With HIV and M184V/I Mutation.
Journal of acquired immune deficiency syndromes (1999) - 1 Apr 2021
Perez-Valero Ignacio, Llibre Josep M, Castagna Antonella, Pulido Federico, Molina Jean-Michel, Esser Stefan, Margot Nicolas, Shao Yongwu, Temme Lauren, Piontkowsky David, McNicholl Ian R, Haubrich Richard
Abstract excerpt
BACKGROUND: The ability of elvitegravir/cobicistat/emtricitabine/tenofovir alafenamide (E/C/F/TAF) to maintain virologic suppression in participants with M184V and/or M184I resistance mutations from historical genotypic reports when switching from a tenofovir disoproxil fumarate-based or abacavir (ABC)-based regimen was investigated. SETTING: Phase IIIb, 48-week, open-label, single-arm, multicenter, clinical...
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