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Article

Polymorphisms in the hypoxia-inducible factor-1α gene confer susceptibility to pancreatic cancer.

Cancer biology & therapy - 1 Sept 2011

Wang Xiuchao, Liu Yingwei, Ren He, Yuan Zhanna, Li Shasha, Sheng Jun, Zhao Tiansuo, Chen Yong, Liu Fenghua, Wang Feng, Huang He, Hao Jihui

Abstract excerpt

The transcription factor hypoxia-inducible factor-1 (HIF-1) has α and β subunits. Recent studies have shown that the HIF-1α gene may have C1772T and G1790A single nucleotide polymorphisms (SNPs). These SNPs may increase the stability and activity of HIF-1α. In the present study, we looked for the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21709439
DOI: 10.4161/cbt.12.5.15982

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21709439-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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