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miR669a and miR669q prevent skeletal muscle differentiation in postnatal cardiac progenitors

27 Jun 2011

Abstract excerpt

Postnatal heart stem and progenitor cells are a potential therapeutic tool for cardiomyopathies, but little is known about the mechanisms that control cardiac differentiation. Recent work has highlighted an important role for microribonucleic acids (miRNAs) as regulators of cardiac and skeletal myogenesis. In this paper, we isolated cardiac progenitors from neonatal β-sarcoglycan (Sgcb)-null mouse hearts affected...

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PMID: 21708977
DOI: 10.1083/jcb.201011099

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