Article
Construction of isogenic gonococci with variable porin structure: effects on susceptibility to human serum and antibiotics.
Molecular microbiology - 1 Jun 1990
Carbonetti N, Simnad V, Elkins C, Sparling P F
Abstract excerpt
Protein I (PI) is the most abundant protein on the gonococcal cell surface and besides its porin function it may have important properties contributing to pathogenicity. By allelic exchange using cloned PI genes from FA19 (PIA) and MS11 (PIB) and a selectable marker introduced closely downstream...
Topics
- Alleles
- Amino Acid Sequence
- Bacterial Outer Membrane Proteins
- Base Sequence
- Cloning, Molecular
- Complement System Proteins
- DNA, Bacterial
- Escherichia coli
- Genes, Bacterial
- Humans
- Lipopolysaccharides
- Microbial Sensitivity Tests