Article
Temporal development of the humoral immune response to surface antigens of Moraxella catarrhalis in young infants.
Vaccine - 5 Aug 2011
Verhaegh Suzanne J C, de Vogel Corné P, Riesbeck Kristian, Lafontaine Eric R, Murphy Timothy F, Verbrugh Henri A, Jaddoe Vincent W V, Hofman Albert, Moll Henriëtte A, van Belkum Alex, Hays John P
Abstract excerpt
The primary Moraxella catarrhalis-specific humoral immune response, and its association with nasopharyngeal colonization, was studied in a cohort of infants from birth to 2 years of age. Results indicated that the levels of antigen-specific IgG, IgA and IgM showed extensive inter-individual variability over time, with IgM and IgA levels to all 9 recombinant domains, from 7 different OMPs, being relatively low...
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