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Repertoire of Naturally Acquired Maternal Antibodies Transferred to Infants for Protection Against Shigellosis

15 Oct 2021

Abstract excerpt

Shigella is the second leading cause of diarrheal diseases, accounting for >200,000 infections and >50,000 deaths in children under 5 years of age annually worldwide. The incidence of Shigella -induced diarrhea is relatively low during the first year of life and increases substantially, reaching its peak between 11 to 24 months of age. This epidemiological trend hints at an early protective immunity of maternal...

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PMID: 34721387
DOI: 10.3389/fimmu.2021.725129

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