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Article

Serum IgG Profiling of Toddlers Reveals a Subgroup with Elevated Seropositive Antibodies to Viruses Correlating with Increased Vaccine and Autoantigen Responses.

Journal of clinical immunology - 1 Jul 2021

Pichilingue-Reto Patricia, Raj Prithvi, Li Quan-Zhen, Dozmorov Igor, Karp David R, Wakeland Edward K, Nelson Morgan, Gruchalla Rebecca S, de la Morena M Teresa, van Oers Nicolai S C

Abstract excerpt

PURPOSE: The human antibody repertoire forms in response to infections, the microbiome, vaccinations, and environmental exposures. The specificity of such antibody responses was compared among a cohort of toddlers to identify differences between seropositive versus seronegative responses. METHODS: An assessment of the serum IgM and IgG antibody reactivities in 197 toddlers of 1- and 2-years of age was performed...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33656624
DOI: 10.1007/s10875-021-00993-w
PMCID: PMC7927113

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