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Involvement of mismatch repair proteins in adaptive responses induced by N-methyl-N'-nitro-N-nitrosoguanidine against γ-induced genotoxicity in human cells.

Mutation research - 1 Aug 2011

Yamamoto Ayumi, Sakamoto Yasuteru, Masumura Kenichi, Honma Masamitsu, Nohmi Takehiko

Abstract excerpt

As humans are exposed to a variety of chemical agents as well as radiation, health effects of radiation should be evaluated in combination with chemicals. To explore combined genotoxic effects of radiation and chemicals, we examined modulating effects of N-methyl-N'-nitro-N-nitrosoguanidine (MNNG), a direct-acting methylating agent, against genotoxicity of γ-radiation. Human lymphoblastoid TK6 cells and its...

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Identifiers

PMID: 21704047
DOI: 10.1016/j.mrfmmm.2011.05.014

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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