Article
Regulation of thiamine biosynthesis in Saccharomyces cerevisiae.
Journal of bacteriology - 1 Oct 1990
Kawasaki Y, Nosaka K, Kaneko Y, Nishimura H, Iwashima A
Abstract excerpt
A pho6 mutant of Saccharomyces cerevisiae, lacking a regulatory gene for the synthesis of periplasmic thiamine-repressible acid phosphatase activity, was found to be auxotrophic for thiamine. The activities of four enzymes involved in the synthesis of thiamine monophosphate were hardly detectable in the crude extract from the pho6 mutant. On the other hand, the activities of these enzymes and thiamine-repressible...
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