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Article

Isolation and characterization of regulatory mutants from Schizosaccharomyces pombe involved in thiamine-regulated gene expression.

Genetics - 1 Mar 1992

Schweingruber A M, Fankhauser H, Dlugonski J, Steinmann-Loss C, Schweingruber M E

Abstract excerpt

Mutants from Schizosaccharomyces pombe deficient in the regulation of thiamine-repressible acid phosphatase have been isolated. Mutants expressing derepressed levels of the enzyme in the presence and absence of thiamine map in three genes, tnr1, tnr2 and tnr3. mRNA levels of the pho4 gene (coding for thiamine repressible acid phosphatase) and another thiamine-regulatable gene, thi3 (coding for a thiamine...

Topics

Acid Phosphatase
Base Sequence
Biological Transport
Blotting, Northern
DNA, Fungal
Epistasis, Genetic
Gene Expression Regulation, Fungal
Genes, Dominant
Genes, Recessive
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Schizosaccharomyces

Thiamine

Source

Open in PubMed Open full text

Identifiers

PMID: 1551569
DOI: 10.1093/genetics/130.3.445
PMCID: PMC1204863

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1551569-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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