Article
Age-related macular degeneration and genetic polymorphisms of glutathione S-transferases M1 (GSTM1) and T1 (GSTT1).
Molecular biology reports - 1 Mar 2012
Othman Hasan, Gholampour Ahmad Reza, Saadat Iraj, Farvardin-Jahromoi Majid, Saadat Mostafa
Abstract excerpt
The aim of this study is to understand the multifactorial causes of age-related macular degeneration (ARMD), and, therefore, it is reasonable to investigate whether genetic polymorphisms of antioxidant enzymes (GSTM1 and GSTT1) contribute to the development of ARMD. This study consisted of 112 subjects (44 females, 68 males) with exudative ARMD, who were recruited from Khalili Hospital ophthalmic clinic in Shiraz...
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