Article
Glutathione-S-transferase M1 and T1 genetic polymorphisms and the risk of cataract development: a study in the Turkish population.
Current eye research - 1 May 2007
Güven Mehmet, Unal Mustafa, Sarici Ahmet, Ozaydin Ahmet, Batar Bahadir, Devranoğlu Kazim
Abstract excerpt
In this study, we aimed to determine the effects of genetic polymorphisms of glutathione-S-transferase M1 (GSTM1) and glutathione-S-transferase T1 (GSTT1) on risk of developing different subtypes of age-related cataract in the Turkish population. Using a multiplex polymerase chain reaction (PCR), GSTM1 and GSTT1 gene polymorphisms were analyzed in 195 patients with age-related cataract (75 patients with cortical,...
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