Article
Glutathione S-transferase M1, GSTT1 and GSTP1 genetic polymorphisms and the risk of age-related macular degeneration.
Ophthalmic research - 1 Jan 2011
Güven Mehmet, Görgün Ebru, Ünal Mustafa, Yenerel Melda, Batar Bahadır, Küçümen Beril, Dinç Umut Aslı, Güven Gülgün S, Ulus Tümer, Yüksel Adnan
Abstract excerpt
PURPOSE: To determine the possible effects of glutathione S-transferase (GST) M1, GSTT1 and GSTP1 genetic polymorphisms on the risk of developing age-related macular degeneration (AMD). PATIENTS AND METHODS: This case-control study included a total of 120 patients with AMD (65 with dry-type AMD and 55 with wet-type AMD) and 198 disease-free controls. GSTM1 and GSTT1 polymorphisms were analyzed by using a...
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