Article
Limited ability to activate protein C confers left atrial endocardium a thrombogenic phenotype: a role in cardioembolic stroke?
Stroke - 1 Sept 2011
Cerveró Jorge, Montes Ramón, España Francisco, Esmon Charles T, Hermida José
Abstract excerpt
BACKGROUND AND PURPOSE: Atrial fibrillation is the most important risk factor for cardioembolic stroke. Thrombi form in the left atrial appendage rather than in the right. The causes of this different thrombogenicity are not well-understood. The goal herein was to compare the activation of the anticoagulant protein C and the thrombomodulin and endothelial protein C receptor/activated protein C receptor expression...
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