Article
Increase and redistribution of cardiac mast cells in auricular thrombosis. Possible role of kit ligand.
Circulation - 15 Jan 1995
Bankl H C, Radaszkiewicz T, Klappacher G W, Glogar D, Sperr W R, Grossschmidt K, Bankl H, Lechner K, Valent P
Abstract excerpt
BACKGROUND: The atrial appendage is a predilection site for thrombus formation. Mast cells (MC) are a rich source of mediators that may be involved in the regulation of thrombus formation. We examined number, distribution, and phenotype of MC in thrombosed versus unaffected auricles to elucidate their possible role in auricular thrombosis (AUTHR). METHODS AND RESULTS: Sections of atrial appendages (AUTHR, n = 14;...
Topics
- Adult
- Aged
- Aged, 80 and over
- Cell Count
- Female
- Heart Atria
- Hematopoietic Cell Growth Factors
- Histamine Release
- Humans
- Immunohistochemistry
- Male