Article
Double-stranded RNA binding proteins DRB2 and DRB4 have an antagonistic impact on polymerase IV-dependent siRNA levels in Arabidopsis.
RNA (New York, N.Y.) - 1 Aug 2011
Pélissier Thierry, Clavel Marion, Chaparro Cristian, Pouch-Pélissier Marie-Noëlle, Vaucheret Hervé, Deragon Jean-Marc
Abstract excerpt
Biogenesis of the vast majority of plant siRNAs depends on the activity of the plant-specific RNA polymerase IV (PolIV) enzyme. As part of the RNA-dependent DNA methylation (RdDM) process, PolIV-dependent siRNAs (p4-siRNAs) are loaded onto an ARGONAUTE4-containing complex and guide de novo DNA methyltransferases to target loci. Here we show that the double-stranded RNA binding proteins DRB2 and DRB4 are required...
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