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Article

Neuraminidase inhibitor R-125489--a promising drug for treating influenza virus: steered molecular dynamics approach.

Biochemical and biophysical research communications - 8 Jul 2011

Mai Binh Khanh, Li Mai Suan

Abstract excerpt

Two neuraminidase inhibitors, oseltamivir and zanamivir, are important drug treatments for influenza. Oseltamivir-resistant mutants of the influenza virus A/H1N1 and A/H5N1 have emerged, necessitating the development of new long-acting antiviral agents. One such agent is a new neuraminidase inhibitor R-125489 and its prodrug CS-8958. An atomic level understanding of the nature of this antiviral agents binding is...

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Identifiers

PMID: 21693105
DOI: 10.1016/j.bbrc.2011.06.057

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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