Article
Gene encoding erythrocyte binding ligand linked to blood stage multiplication rate phenotype in Plasmodium yoelii yoelii.
Proceedings of the National Academy of Sciences of the United States of America - 28 Apr 2009
Pattaradilokrat Sittiporn, Culleton Richard L, Cheesman Sandra J, Carter Richard
Abstract excerpt
Variation in the multiplication rate of blood stage malaria parasites is often positively correlated with the severity of the disease they cause. The rodent malaria parasite Plasmodium yoelii yoelii has strains with marked differences in multiplication rate and pathogenicity in the blood. We have used genetic analysis by linkage group selection (LGS) to identify genes that determine differences in multiplication...
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