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Article

microRNA regulation of expression of the cystic fibrosis transmembrane conductance regulator gene

4 Jul 2011

Abstract excerpt

The CFTR (cystic fibrosis transmembrane conductance regulator) gene shows a complex temporal and spatial pattern of expression that is controlled by multiple cis-acting elements interacting with the basal promoter. Although significant progress has been made towards understanding these genomic elements, there have been no reports of post-transcriptional regulation of CFTR by miRNAs (microRNAs). In the present...

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PMID: 21689072
DOI: 10.1042/bj20110672

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