Article
Use of high-dose ganciclovir for a resistant cytomegalovirus infection due to UL97 mutation.
Transplant infectious disease : an official journal of the Transplantation Society - 1 Apr 2008
West P, Schmiedeskamp M, Neeley H, Oberholzer J, Benedetti E, Kaplan B
Abstract excerpt
Cytomegalovirus (CMV) infection is a major complication following solid organ transplantation resulting in significant morbidity and mortality. The guidelines published in 2004 have recommendations for therapy; however, the frequency of resistant CMV infection is increasing and therapy is not clearly defined. There are a few alternatives to ganciclovir such as foscarnet, cidofovir, and leflunomide; however, their...
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