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Article

Genetic evidence that Neisseria gonorrhoeae produces specific receptors for transferrin and lactoferrin.

Journal of bacteriology - 1 Sept 1990

Blanton K J, Biswas G D, Tsai J, Adams J, Dyer D W, Davis S M, Koch G G, Sen P K, Sparling P F

Abstract excerpt

Transferrin (TF) and lactoferrin (LF) are probably the major sources of iron (Fe) for Neisseria gonorrhoeae in vivo. We isolated mutants of N. gonorrhoeae FA19 that were unable to grow with Fe bound to either TF (TF-) or LF (LF-) or to both TF and LF ([TF LF]-). The amount of Fe internalized by each of the mutants was reduced to background levels from the relevant iron source(s). The wild-type parent strain...

Topics

Binding, Competitive
Chromosome Mapping
DNA, Bacterial
Genotype
Iron
Kinetics
Lactoferrin
Ligands
Mutation
Neisseria gonorrhoeae
Phenotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Receptors, Cell Surface

Receptors, Transferrin

Transferrin

Transformation, Bacterial

Source

Open in PubMed Open full text

Identifiers

PMID: 2168377
DOI: 10.1128/jb.172.9.5225-5235.1990
PMCID: PMC213184

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2168377-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Genetic evidence that Neisseria gonorrhoeae produces specific receptors for transferrin and lactoferrin.PMID 2168377Read ↗

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