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Article

Cloning and functional characterization of Neisseria gonorrhoeae tonB, exbB and exbD genes.

Molecular microbiology - 1 Apr 1997

Biswas G D, Anderson J E, Sparling P F

Abstract excerpt

Neisseria gonorrhoeae is able to utilize iron (Fe) from a variety of sources including transferrin (TF) and lactoferrin (LF). To gain insight into the molecular mechanisms used by gonococci to scavenge Fe from TF and LF, we cloned a 3.5 kb segment of wild-type DNA that repaired the defect in tlu...

Topics

Bacterial Proteins
Base Sequence
Chromosome Mapping
Cloning, Molecular
DNA Repair
DNA, Bacterial
Escherichia coli Proteins
Hemoglobins
Humans
Iron
Lactoferrin
Ligands
Membrane Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

Mutation

Neisseria gonorrhoeae

Phenotype

Transferrin

Source

Identifiers

PMID: 9140974
DOI: 10.1046/j.1365-2958.1997.3421692.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9140974-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Cloning and functional characterization of Neisseria gonorrhoeae tonB, exbB and exbD genes.PMID 9140974Read ↗

TonB-Dependent Transporters Expressed by Neisseria gonorrhoeaeSemantic proximity Read ↗

Mechanisms of iron acquisition by the human pathogens Neisseria Meningitidis and Neisseria GonorrhoeaeSemantic proximity Read ↗

Characterization of lbpA, the structural gene for a lactoferrin receptor in Neisseria gonorrhoeaeSemantic proximity Read ↗

The fbpABC operon is required for Ton-independent utilization of xenosiderophores by Neisseria gonorrhoeae strain FA19.Semantic proximity Read ↗

Gonococcal transferrin-binding protein 1 is required for transferrin utilization and is homologous to TonB-dependent outer membrane receptorsSemantic proximity Read ↗

<i>Neisseria gonorrhoeae</i> requires expression of TonB and the putative transporter TdfF to replicate within cervical epithelial cellsSemantic proximity Read ↗

Evidence of Fe3+ interaction with the plug domain of the outer membrane transferrin receptor protein of Neisseria gonorrhoeae: implications for Fe transport.Semantic proximity Read ↗

Neisseria gonorrhoeae bacterioferritin: structural heterogeneity, involvement in iron storage and protection against oxidative stress.Semantic proximity Read ↗

Investigating the importance of selected surface-exposed loops in HpuB for hemoglobin binding and utilization by Neisseria gonorrhoeae.Semantic proximity Read ↗

Gonococcal transferrin-binding protein 2 facilitates but is not essential for transferrin utilizationSemantic proximity Read ↗

Genetic evidence that Neisseria gonorrhoeae produces specific receptors for transferrin and lactoferrin.Semantic proximity Read ↗

Identification of the Iron-Responsive Genes of Neisseria gonorrhoeae by Microarray Analysis in Defined MediumSemantic proximity Read ↗

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