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<i>Neisseria gonorrhoeae</i> requires expression of TonB and the putative transporter TdfF to replicate within cervical epithelial cells

13 Oct 2006

Abstract excerpt

Neisseria gonorrhoeae has evolved a repertoire of iron acquisition systems that facilitate essential iron uptake in the human host. Acquisition of iron requires both the energy-harnessing cytoplasmic membrane protein, TonB, as well as specific outer membrane TonB-dependent transporters (TdTs.) Survival within host epithelial cells is important to the pathogenesis of gonococcal disease and may contribute to the...

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PMID: 17038122
DOI: 10.1111/j.1365-2958.2006.05429.x

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<i>Neisseria gonorrhoeae</i> requires expression of TonB and the putative transporter TdfF to replicate within cervical epithelial cellsPMID 17038122Read ↗

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Neisseria gonorrhoeae Modulates Iron-Limiting Innate Immune Defenses in MacrophagesSemantic proximity Read ↗

Dual species transcriptomics reveals core metabolic and immunologic processes in the interaction between primary human neutrophils and <i>Neisseria gonorrhoeae</i> strainsSemantic proximity Read ↗

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Genetic evidence that Neisseria gonorrhoeae produces specific receptors for transferrin and lactoferrin.Semantic proximity Read ↗

Gonococcal transferrin-binding protein 1 is required for transferrin utilization and is homologous to TonB-dependent outer membrane receptorsSemantic proximity Read ↗

Identification of discrete domains within gonococcal transferrin-binding protein A that are necessary for ligand binding and iron uptake functions.Semantic proximity Read ↗

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