Article
Two genetic variants in prostate stem cell antigen and gastric cancer susceptibility in a Chinese population.
Molecular carcinogenesis - 1 Dec 2009
Wu Chen, Wang Guanghai, Yang Ming, Huang Liming, Yu Dianke, Tan Wen, Lin Dongxin
Abstract excerpt
Genetic factors play important roles in pathogenesis of human cancer. A recent genome-wide association study (GWAS) linked two single nucleotide polymorphisms (SNPs) in prostate stem cell antigen (PSCA), rs2294008C>T and rs2976392G>A, to risk of diffuse-type of gastric cancer in Japanese and Korean populations. We hypothesized that these two SNPs are also associated with risk of gastric cancer in Chinese...
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