Article
Genetic variation of PSCA gene is associated with the risk of both diffuse- and intestinal-type gastric cancer in a Chinese population.
International journal of cancer - 1 Nov 2010
Lu Yan, Chen Jianjian, Ding Yanbing, Jin Guangfu, Wu Juan, Huang Hua, Deng Bin, Hua Zhaolai, Zhou Yan, Shu Yongqian, Liu Ping, Hu Zhibin, Shen Jing, Xu Yaochu, Shen Hongbing
Abstract excerpt
Prostate stem cell antigen (PSCA), a member of the LY-6/Thy-1 family of glycosylphosphatidylinositol-anchored cell surface proteins, is considered to be involved in the cell-proliferation inhibition and/or cell-death induction activity. Two single nucleotide polymorphisms (SNPs) (rs2976392 and rs2294008) in the PSCA gene were recently identified as the susceptibility loci of gastric cancer, especially in diffuse...
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