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Article

Role of ox-PAPCs in the differentiation of mesenchymal stem cells (MSCs) and Runx2 and PPARγ2 expression in MSCs-like of osteoporotic patients.

PloS one - 1 Jan 2011

Valenti Maria Teresa, Garbin Ulisse, Pasini Andrea, Zanatta Mirko, Stranieri Chiara, Manfro Stefania, Zucal Chiara, Dalle Carbonare Luca

Abstract excerpt

BACKGROUND: Mesenchymal stem cells (MSCs) can differentiate into osteoblasts and adipocytes and conditions causing bone loss may induce a switch from the osteoblast to adipocyte lineage. In addition, the expression of Runx2 and the PPARγ2 transcription factor genes is essential for cellular commitment to an osteogenic and adipogenic differentiation, respectively. Modified lipoproteins derived from the oxidation...

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Source

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Identifiers

PMID: 21674037
DOI: 10.1371/journal.pone.0020363
PMCID: PMC3108593

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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