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Article

Mutations to the probe of Cobas TaqMan HIV-1 ver. 1.0 assay causing undetectable viral load in a patient with acute HIV-1 infection.

Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy - 1 Dec 2011

Yotsumoto Mihoko, Shinozawa Keiko, Yamamoto Yasuyuki, Sugiura Wataru, Miura Toshiaki, Fukutake Katsuyuki

Abstract excerpt

We encountered a human immunodeficiency virus (HIV)-1 in which the viral load was undetectable with the Cobas TaqMan HIV-1 ver. 1.0 (CTM v.1.0) in a patient with acute HIV-1 infection. The CTM v.1.0 assay showed more than 1,000-fold underestimation compared with the subsequent Cobas Amplicor Monitor v.1.5 assay. Because five mismatches to the CTM v.1.0 assay probe in the HIV-1 virus in the patient were disclosed...

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Identifiers

PMID: 21671012
DOI: 10.1007/s10156-011-0263-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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